Cell Biology
Faculty and Research Interests
Venkat Venkataraman, PhD
Assistant Professor
Science Center 220
856-566-6418
venkatar@umdnj.edu
Education
Indian Institute of Science,
PhD, 1991.
Research Interests
My major area of interest is cell communication – how cells receive signals and decipher them to respond in an appropriate fashion. I am particularly interested in communication in neuronal cells – both central and peripheral. My current programs, based on this work, include:
- Signaling in neurodegenerative diseases: I am using Alzheimer’s disease as a model to understand the signaling events that occur during neuronal degeneration.
- Signaling in biological clocks: I am studying the signaling molecules in defining the circadian rhythm in mammals using rat and mouse as model systems.
- Signaling in Fascia: I am studying the role of calcium signaling in the fascia .
- Retinal signaling: I am investigating the role of membrane guanylate cyclases and NCS proteins in non-photoreceptor signaling in the retina
Recent Publications
- Ragunath C, Manuel SG, Venkataraman V, Sait HB, Kasinathan C, Ramasubbu N Probing the role of aromatic residues at the secondary saccharide-binding sites of human salivary alpha-amylase in substrate hydrolysis and bacterial binding. J Mol Biol 2008 Dec 31;384(5):1232-48. Epub 2008 Oct 14.
- Venkataraman V, Duda T, Ravichandran S, Sharma RK. Neurocalcin delta Modulation of ROS-GC1, a New Model of Ca2+ Signaling. Biochemistry, 47 (25), 6590–6601, 2008.
- Clifford PM, Zarrabi S, Siu G, Kinsler KJ, Kosciuk MC, Venkataraman V, D'Andrea MR, Dinsmore S, Nagele RG. Abeta peptides can enter the brain through a defective blood-brain barrier and bind selectively to neurons. Brain Res. 2007 Apr 20;1142:223-36. Epub 2007 Jan 27.
- Duda T, Venkataraman V, Ravichandran S, Sharma RK. ATP-regulated module (ARM) of the atrial natriuretic factor receptor guanylate cyclase. Peptides. 26, 969-984, 2005.
- Sharma RK, Duda T, Venkataraman V, Koch K-W. Calcium-modulated membrane guanylate cyclase, ROS-GC transduction machinery in sensory neurons: a universal concept. Curr Topics Biochem. Res. 6, 111 – 144, 2004.
- Duda T, Fik-Rymarkiewicz E, Venkataraman V, Krishnan R, Sharma RK. The Calcium-Sensor Guanylate Cyclase Activating Protein Type 2 Specific Site in Rod Outer Segment Membrane Guanylate Cyclase Type 1. Biochemistry. 44, 7336-7345, 2005.
- Krishnan A, Venkataraman V, Fik-Rymarkiewicz E, Duda T, Sharma RK. Structural, biochemical, and functional characterization of the calcium sensor neurocalcin delta in the inner retinal neurons and its linkage with the rod outer segment membrane guanylate cyclase transduction system. Biochemistry. 43, 2708-2723, 2004. - Equal contribution
