Faculty and Research Interests

Dimitri Pestov, PhD

Assistant Professor
Department of Cell Biology
Science Center 204A
2 Medical Center Drive
Stratford, NJ 08084
856-566-6-6904 (office)
856-566-6195 (fax)
pestovdg@umdnj.edu

Education:

University of Illinois, PhD, 1997.

Research Interests:

Ribosome biogenesis and function in mammalian cells; understanding how the accuracy of ribosome assembly is controlled at the molecular level and how defects in this process contribute to pathological conditions.

Relevant Publications

1. Lapik YR, Misra JM, Lau LF, Pestov DG. (2007) Restricting Conformational Flexibility of the Switch II Region Creates a Dominant-Inhibitory Phenotype in Obg GTPase Nog1. Mol Cell Biol. 2007 Nov;27(21):7735-44. Epub 2007 Sep 4.

2. Gratenstein K, Heggestad AD, Fortun J, Notterpek L, Pestov DG, Fletcher BS. (2005) The WD-repeat protein GRWD1: potential roles in myeloid differentiation and ribosome biogenesis. Genomics. 2005 Jun;85(6):762-73.

3. Lapik YR, Fernandes CJ, Lau LF, Pestov DG. (2004) Physical and functional interaction between Pes1 and Bop1 in mammalian ribosome biogenesis. Mol Cell. 2004 Jul 2;15(1):17-29.

4. Strezoska Z, Pestov DG, Lau LF. (2002) Functional inactivation of the mouse nucleolar protein Bop1 inhibits multiple steps in pre-rRNA processing and blocks cell cycle progression. J Biol Chem. 2002 Aug 16;277(33):29617-25. Epub 2002 Jun 4.